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Vaccine from Pfizer / BioNTech appears less effective than Moderna - Observer

Vaccine from Pfizer / BioNTech appears less effective than Moderna – Observer

mRNA vaccines from Moderna and Pfizer/BioN Tech, It remains highly effective in preventing serious diseases. (leading to acceptance), even in the presence of a delta variant, but both reduced their effectiveness in preventing transmission of this variant, Mayo Clinic researchers concluded in an article published On a pre-publication platform that has not been reviewed by independent scholars.

Another study, conducted in Canadian homes, revealed a difference in the effectiveness of the Pfizer/BioNTech vaccine compared to Moderna.

From January to July 2021, the period during which the Mayo Clinic investigation was conducted, both vaccines were effective in preventing infection: 86% for Modern and 76% for Pfizer, compared with unvaccinated people. However, in July, when the delta variant became dominant (prevalence of 70%) in Minnesota, where the study was conducted, Efficacy in preventing infection fell to 76% in Moderna and 42% in Pfizer/BioNTech.

Individuals vaccinated with mRNA-1273 [vacina da Moderna] They were less likely to get an infection. [com SARS-CoV-2] During the study period,” the authors write.

Remember that the primary goal of vaccines, when they were developed, was the prevention of severe COVID-19 disease, hospitalizations and deaths, and vaccines remain highly effective in achieving these goals.

During the study period, Moderna showed a 91.6% efficacy and 85% Pfizer/BioNTech in preventing hospitalization With Covid-19 and 93.3% and 87%, respectively, in preventing admission to intensive care. During the same period, no one who was vaccinated died.

Moreover, among people who became infected despite being vaccinated, researchers No differences were found in disease severity or disease progression Comparing those vaccinated with Moderna or Pfizer/BioNTech.

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You are Residents of vaccinated homes produced five to six times fewer neutralizing antibodies of employees vaccinated in the four residential buildings of the elderly in Ontario (Canada), taking into account the variant of the virus against which vaccines were produced (D614G) – which has taken over Portugal, Europe and several other countries in 2020.

In addition to the population vaccinated from Pfizer/BioNTech produced about four times fewer neutralizing antibodies Of those who received the Moderna vaccine, study authors write published It is on a pre-publication platform and has not yet been reviewed by independent scholars.

The researchers also found that 38% of the population who took the Pfizer/BioNTech vaccine Failed to develop antibodies capable of neutralizing the beta variant (I originated in South Africa) and 29% of those who took this vaccine did not have antibodies against the gamma variant (which appeared in Manaus, Brazil). Those vaccinated with Moderna and the staff were more successful in producing this type of antibody.

In general, the second dose of the vaccine allowed the elderly to elicit an immune response equivalent to those who had a natural infection and recovered.